Pambuyo pachimake kapena kuwonongeka kwa chotchinga cha epidermal, njira yokonza yokonza khungu imathandizira kupanga kwa Keratinocyte Izi zimakondanso za zizindikiro zowuma pakhungu.
Kutupa kwako komweko kungakulenso khungu lakuuma, makamaka, kusokonekera kwa chotchinga chachikulu kumalimbikitsa cyntuches yotupa, monga Il-1E-sn-1henc, 1henc Atakopeka ndi malo owuma, mukafika komwe akupita, neutrophils secrete leustose, cathepsin g, protegenin g, protegenase 3, ndikupanga mapulotetekecyte mu Keratinocytes. Zotsatira Zotheka Zochita Zochita Zoopsa: 1. Kuwonongeka kwa cell; 2. Kumasulidwa kwa ma cytokines ofiira; 3. Kuwonongeka msanga kwa ma cell-cell omwe amalimbikitsa cell mutosis. Protenyoctic enzyme ntchito pakhungu lowuma, lomwe lingakhudzenso mitsempha yaluso mu epidermis, imagwirizanitsidwa ndi pruritus ndi zowawa. Kusintha kwapamwamba kwa tranexamic acid ndi α1-antitrryprin (protease inrosito) mpaka xerosis ndi ogwira mtima, akuwonetsa kuti Xeroderma amagwirizana ndi protelyme ntchito.
Wowuma epirmis amatanthauza kutichotchinga cha pakhungu chimasokonezeka, Lipids ndi otayika, mapuloteni amachepetsedwa, ndipo matupi otupa a komwe amatulutsidwa.Khungu louma lomwe limayambitsidwa ndi kuwonongeka kwa zotchingandizosiyana ndi zouma zomwe zimayambitsidwa ndi katulutsidwe ka sebum yochepetsedwa, ndipo zotsatira za zowonjezera za liid zosavuta zimalephera kukwaniritsa zoyembekezera. Kunyowa zopangidwa ndi zotchinga zotchinga sikuyenera kungowonjezera zifukwa zogwirizira, monga ma ceramida, komanso magawano a antilamida, potero amachepetsa kusiyanitsa kwa Keratinocytes. Chotchinga cham'khungu nthawi zambiri chimaphatikizidwa ndi pruritus, ndipo kuwonjezera kwa antipruritic Addoctics kuyenera kuganiziridwa.
Post Nthawi: Jun-10-2022
