Kukalamba Pakhungu ——Skincare

Mahomoni amachepa ndi zaka, kuphatikizapo estrogen, testosterone, dehydroepiandrosterone sulfate, ndi hormone ya kukula.Zotsatira za mahomoni pakhungu ndizochulukirapo, kuphatikiza kuchuluka kwa kolajeni, kuchuluka kwa khungu, komanso kutulutsa bwino kwapakhungu.Pakati pawo, chikoka cha estrogen chikuwonekera kwambiri, koma makina a chikoka chake pa maselo akadali osadziwika bwino.Zotsatira za estrogen pakhungu zimazindikirika makamaka ndi keratinocytes za epidermis, fibroblasts ndi melanocytes za dermis, komanso maselo a tsitsi ndi zotupa za sebaceous.Pamene mphamvu ya amayi yopanga estrogen imachepa, kukalamba kwa khungu kumathamanga.Kuperewera kwa hormone estradiol kumachepetsa ntchito ya basal wosanjikiza wa epidermis ndi kuchepetsa kaphatikizidwe wa kolajeni ndi zotanuka ulusi, zonse zofunika kuti akhalebe bwino khungu elasticity.Kutsika kwa ma estrogen omwe ali ndi postmenopausal sikungowonjezera kuchepa kwa collagen ya khungu, komanso kagayidwe ka maselo a dermal amakhudzidwa ndi ma postmenopausal otsika otsika a estrogen, ndipo kusintha kumeneku kungasinthidwe mwamsanga pogwiritsa ntchito mutu wa estrogen.Kuyesera kwatsimikizira kuti estrogen yam'mutu yachikazi imatha kukulitsa kolajeni, kusunga makulidwe a khungu, ndikusunga chinyontho cha khungu ndi ntchito yotchinga ya stratum corneum powonjezera acidic glycosaminoglycans ndi asidi hyaluronic, kuti khungu likhale lokhazikika.Zitha kuwoneka kuti kuchepa kwa ntchito ya endocrine system ndi chimodzi mwazinthu zofunika kwambiri pakukalamba kwa khungu.

Kuchepetsa katulutsidwe ka minyewa ya pituitary, adrenal, ndi gonads kumathandizira kusintha kwa thupi ndi khungu la phenotype ndi machitidwe okhudzana ndi ukalamba.Miyezo ya seramu ya 17β-estradiol, dehydroepiandrosterone, progesterone, kukula kwa hormone, ndi kutsika kwawo kwa hormone insulin kukula factor (IGF) -ndimachepetsa ndi zaka.Komabe, milingo ya kukula kwa hormone ndi IGF-I mu seramu yamphongo inachepa kwambiri, ndipo kuchepa kwa ma hormone m'magulu ena akhoza kuchitika pa msinkhu wakale.Mahomoni amatha kukhudza mawonekedwe a khungu ndi magwiridwe antchito, kuwonongeka kwa khungu, machiritso, cortical lipogenesis, ndi metabolism yapakhungu.Estrogen m'malo mankhwala amatha kupewa kusintha kwa thupi komanso ukalamba wa khungu.

——“Skin Epiphysiology” Yinmao Dong, Laiji Ma, Chemical Industry Press

Choncho, pamene tikukula, chidwi chathu pazochitika za khungu chiyenera kuwonjezeka pang'onopang'ono.Titha kugwiritsa ntchito akatswirizida zowunikira khungukuyang'ana ndikuwonetseratu siteji ya khungu, kulosera mavuto a khungu mwamsanga, ndikuchita nawo mwakhama.