Mapangidwe ndi Zomwe Zimakhudza Ma Microbes a Khungu

Mapangidwe ndi Zomwe ZimayambitsaMa Microbes a Pakhungu

1. Mapangidwe a tizilombo toyambitsa matenda

Tizilombo ta pakhungu ndi ziwalo zofunika kwambiri pakhungu, ndipo zomera zomwe zili pakhungu zimatha kugawidwa kukhala mabakiteriya okhala ndi mabakiteriya osakhalitsa. Mabakiteriya okhalamo ndi gulu la tizilombo tating'onoting'ono tomwe timapanga khungu lathanzi, kuphatikiza Staphylococcus, Corynebacterium, Propionibacterium, Acinetobacter, Malassezia, Micrococcus, Enterobacter, ndi Klebsiella. Mabakiteriya osakhalitsa amatanthawuza gulu la tizilombo toyambitsa matenda zomwe timapeza pokhudzana ndi chilengedwe chakunja, kuphatikizapo Staphylococcus aureus, Streptococcus hemolyticus ndi Enterococcus, etc. Ndiwo mabakiteriya akuluakulu omwe amayambitsa matenda a khungu. Mabakiteriya ndi omwe amapezeka kwambiri pakhungu, komanso pakhungu pali mafangasi. Kuchokera pamlingo wa phylum, sewero latsopano pakhungu limapangidwa makamaka ndi ma phyla anayi, omwe ndi Actinobacteria, Firmicutes, Proteobacteria ndi Bacteroidetes. Kuchokera pamtundu wamtundu, mabakiteriya omwe ali pakhungu amakhala makamaka Corynebacterium, Staphylococcus ndi Propionibacterium. Mabakiteriyawa amathandiza kwambiri kuti khungu likhale ndi thanzi.

2. Zomwe zimakhudza khungu la microecology

(1) Host factor

Monga zaka, jenda, malo, zonse zimakhudza tizilombo toyambitsa matenda.

(2) Zowonjezera pakhungu

Zolowa ndi zomangira pakhungu, kuphatikiza zotupa za thukuta (thukuta ndi apocrine glands), zotupa za sebaceous, ndi zitsitsi zatsitsi, zimakhala ndi maluwa awoawo.

(3) Kujambula kwapakhungu.

Topographical kusintha kwa khungu pamwamba zimachokera kumadera osiyanasiyana a khungu anatomy. Njira zozikidwa pa chikhalidwe zimaphunzira kuti madera osiyanasiyana a topographical amathandiza tizilombo tosiyanasiyana.

(4) Ziwalo za thupi

Njira zachilengedwe zama cell zimazindikira lingaliro la mitundu yosiyanasiyana ya mabakiteriya, ndikugogomezera kuti khungu la microbiota limadalira malo a thupi. Kukhazikika kwa mabakiteriya kumadalira malo akhungu ndipo kumalumikizidwa ndi chilengedwe chonyowa, chowuma, chokhala ndi sebaceous microenvironment, etc.

(5) Kusintha kwa nthawi

Njira zachilengedwe za mamolekyulu zidagwiritsidwa ntchito pophunzira kusintha kwakanthawi komanso kwapang'onopang'ono kwa khungu la microbiota, zomwe zidapezeka kuti zikugwirizana ndi nthawi ndi malo a sampuli.

(6) pH kusintha

Kumayambiriro kwa 1929, Marchionini adatsimikizira kuti khungu liri ndi acidic, motero anakhazikitsa lingaliro lakuti khungu liri ndi "countercoat" yomwe ingalepheretse kukula kwa tizilombo toyambitsa matenda ndi kuteteza thupi ku matenda, omwe akhala akugwiritsidwa ntchito pa kafukufuku wa dermatological mpaka lero.

(7) Zinthu zakunja - kugwiritsa ntchito zodzoladzola

Pali zinthu zambiri exogenous zomwe zimakhudzakhungu la microecology, monga kutentha, chinyezi, mpweya wabwino, zodzoladzola, ndi zina zotero za chilengedwe chakunja. Pakati pazinthu zambiri zakunja, zodzoladzola ndi chimodzi mwazinthu zofunika kwambiri pakhungu la microecology m'malo ena a thupi la munthu chifukwa cholumikizana pafupipafupi ndi zodzoladzola.