Whitening Cosmetics ndi Pigment Metabolism

Whitening Zodzoladzola ndiPigmentMetabolism

Melanin anabolism amagawidwa mu nthawi zosiyanasiyana.Asayansi akukhulupirira kuti ndizotheka kuphunzira zopangira zoyera ndikugwira ntchito nthawi zosiyanasiyana za metabolic.

(1) Gawo loyambirira la kaphatikizidwe ka melanin

① Kusokoneza kalembedwe ndi/kapena glycosylation ya tyrosinase;② Imaletsa owongolera pakupanga tyrosinase;③ Kuwongolera pambuyo-kulemba kwa tyrosinase.

(2) Melanin synthesis nthawi
Monga ma enzyme ofunikira komanso kuchepetsa kuchuluka kwa melanin kaphatikizidwe, ma tyrosinase inhibitors ndiye njira yayikulu yofufuzira ndi chitukuko pakadali pano.Popeza zinthu zambiri zoyera monga phenol ndi catechol zotuluka m'mapangidwe amafanana ndi tyrosine ndi dopa, zoyera zowunikiridwa nthawi zambiri zimasankhidwa kukhala zoletsa zoletsa mpikisano kapena zopikisana za tyrosinase.

(3) Mochedwa siteji ya kaphatikizidwe melanin

① Imalepheretsa kusamutsa kwa melanosome;zinthu zomwe zimakhala ndi serine protease inhibitory effect, monga rwj-50353, zimapewatu mtundu wa epidermal pigmentation wopangidwa ndi UBV;soya trypsin inhibitor imakhala yoyera bwino koma ilibe mphamvu pa kawopsedwe ka maselo a pigment;Niacinamide, imatha kulepheretsa kufalikira kwa melanocyte pakati pa melanocyte ndi keratinocyte;② Kubalalika kwa melanin ndi kagayidwe kake, α-hydroxy acid, mafuta aulere acid ndi retinoic acid, kumalimbikitsa kukonzanso kwa maselo ndikulimbikitsa ma melaninized keratinocyte kuchotsa.

Dziwani kuti kafukufuku ndi kugwiritsa ntchito whitening zinthu zochokera pamwamba melanin kagayidwe si oyenera kupewa ndi kuchiza okalamba plaques.Popeza kuti njira yopangira zolembera za senile imagwirizana ndi mapangidwe a lipofuscin, zinthu zogwira ntchito za antioxidative zimagwiritsidwa ntchito pochedwetsa ndi kubweza zolembera za senile.